Research records indexed for IGF-1 DES
This page carries 12 of the 179 records that the literature query returned for IGF-1 DES, selected by citation count and preferring records that name the compound in their title. It is a selection, not a complete index, and the 167 records it does not carry are not represented here. Every row resolves to a real identifier and names the study model, so no finding reads as a human claim by default. The compound page is IGF-1 DES.
Indexed records
| Record | Year | Study type | Model | n as stated | What it reported |
|---|---|---|---|---|---|
| Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling pmid:20042609 | 2010 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. compound named in the abstract, not the title. study model from MeSH "Rats". subject headings: Bone And Bones; Osteoblasts; Nitric Oxide; Estradiol; Insulin-Like Growth Factor I. |
| Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-I pmid:18393172 | 2008 | Comparative Study, Research Support, Non-U.S. Gov't | other | Not stated | Indexed as comparative study, research support, non-u.s. gov't. compound named in the abstract, not the title. study model from MeSH "Humans" with no interventional publication type. subject headings: Tumor Cells, Cultured; Osteosarcoma; Breast Neoplasms; Insulin; Insulin, Long-Acting. |
| The quantitative and functional relation between insulin-like growth factor-I (IGF) and IGF-binding proteins during human osteoarthritis pmid:18050312 | 2008 | Research Support, Non-U.S. Gov't, research-article | other | Not stated | Indexed as research support, non-u.s. gov't, research-article. compound named in the abstract, not the title. study model from MeSH "Humans" with no interventional publication type. subject headings: Cartilage, Articular; Osteoarthritis, Knee; Osteoarthritis, Hip; Insulin-Like Growth Factor I; Insulin-Like Growth Factor Binding Protein 3. |
| Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis pmid:10702797 | 2000 | Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, u.s. gov't, p.h.s., research support, non-u.s. gov't. study model from MeSH "Mice, Inbred C57bl". subject headings: Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Transgenic; Mammary Neoplasms, Experimental. |
| Effect of insulin-like growth factor (IGF)-I and Des (1-3) IGF-I on the level of IGF binding protein-3 and IGF binding protein-3 mRNA in cultured porcine embryonic muscle cells pmid:10048587 | 1999 | Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S. | other | Not stated | Indexed as research support, non-u.s. gov't, research support, u.s. gov't, non-p.h.s.. study model from MeSH "Animals" with no rodent species heading. subject headings: Muscles; Cells, Cultured; Swine; Insulin-Like Growth Factor I; Peptide Fragments. |
| Des(1-3)IGF-I: a truncated form of insulin-like growth factor-I pmid:8930132 | 1996 | Review | other | Not stated | Indexed as review. study model from MeSH "Animals" with no rodent species heading. subject headings: Cattle; Swine; Insulin-Like Growth Factor I; Peptide Fragments; Protein Processing, Post-Translational. |
| Enzymatic conversion of IGF-I to des(1-3)IGF-I in rat serum and tissues: a further potential site of growth hormone regulation of IGF-I action pmid:7561610 | 1995 | Comparative Study, Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as comparative study, research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Myocardium; Liver; Testis; Kidney; Spleen. |
| Des (1-3) IGF-I potently enhances differentiated cell growth in olfactory bulb organ culture pmid:7779409 | 1994 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Brain; Olfactory Bulb; Neurons; Rats, Sprague-Dawley; Glial Fibrillary Acidic Protein. |
| des-(1-3)-IGF-I, an insulin-like growth factor analog used to mimic a potential IGF-II autocrine loop, promotes the differentiation of human colon-carcinoma cells pmid:1281142 | 1992 | Research Support, Non-U.S. Gov't | other | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Humans" with no interventional publication type. subject headings: Tumor Cells, Cultured; Colonic Neoplasms; Cell Transformation, Neoplastic; Receptor, IGF Type 1; Insulin-Like Growth Factor I. |
| IGF-I and the truncated analogue des-(1-3)IGF-I enhance growth in rats after gut resection pmid:1996625 | 1991 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats, Inbred Strains". subject headings: Ileum; Jejunum; Rats, Inbred Strains; Body Weight; Nitrogen. |
| Plasma clearance and tissue distribution of labelled insulin-like growth factor-I (IGF-I), IGF-II and des(1-3)IGF-I in rats pmid:2005410 | 1991 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats, Inbred Strains". subject headings: Intestinal Mucosa; Gastric Mucosa; Liver; Kidney; Adrenal Glands. |
| Increased weight gain, nitrogen retention and muscle protein synthesis following treatment of diabetic rats with insulin-like growth factor (IGF)-I and des(1-3)IGF-I pmid:1710892 | 1991 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats, Inbred Strains". subject headings: Muscles; Rats, Inbred Strains; Diabetes Mellitus, Experimental; Weight Gain; Nitrogen. |
Where this page sits
Compound page: IGF-1 DES. Class: Growth factors and growth hormone-derived compounds.
Retrieved 2026-10-12.
Sources
- Drugs@FDA application register query for this compound, no application records returned. U.S. Food and Drug Administration, openFDA drugsfda endpoint (2026). fda:igf-1-des
- Insulin-like growth factor (IGF)-binding proteins inhibit the biological activities of IGF-1 and IGF-2 but not des-(1-3)-IGF-1. The Biochemical journal (1989). pmid:2539101
- Enzymatic conversion of IGF-I to des(1-3)IGF-I in rat serum and tissues: a further potential site of growth hormone regulation of IGF-I action. The Journal of endocrinology (1995). pmid:7561610
- IGF-I and the truncated analogue des-(1-3)IGF-I enhance growth in rats after gut resection. The American journal of physiology (1991). pmid:1996625
- Cooperative interaction between mutant p53 and des(1-3)IGF-I accelerates mammary tumorigenesis. Oncogene (2000). pmid:10702797
- Age-related differences in the des IGF-I-mediated activation of Akt-1 and p70 S6K in mouse skeletal muscle. Mechanisms of ageing and development (2003). pmid:12875741
On each stated value was matched to the record cited for it. That is record matching, not an appraisal of the research. Compiled and checked by: Peptide Monographs editorial desk. No qualified clinical reviewer.