Research records indexed for Larazotide
This page carries 12 of the 45 records that the literature query returned for Larazotide, selected by citation count and preferring records that name the compound in their title. It is a selection, not a complete index, and the 33 records it does not carry are not represented here. Every row resolves to a real identifier and names the study model, so no finding reads as a human claim by default. The compound page is Larazotide.
Indexed records
| Record | Year | Study type | Model | n as stated | What it reported |
|---|---|---|---|---|---|
| Viral spike antigen clearance and augmented recovery in children with post-COVID multisystem inflammatory syndrome treated with larazotide pmid:40737433 | 2025 | Clinical Trial, Phase II, Research Support, Non-U.S. Gov't | human trial | Not stated | Indexed as clinical trial, phase ii, research support, non-u.s. gov't. study model from MeSH "Humans" with publication type "clinical trial, phase ii". subject headings: Antigens, Viral; Child, Preschool; Systemic Inflammatory Response Syndrome; Spike Glycoprotein, Coronavirus; COVID-19. |
| Antibacterial hyaluronic acid hydrogel with sustained release of larazotide as effective colitis treatment pmid:40915363 | 2025 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Mice, Inbred C57bl". subject headings: Intestinal Mucosa; Caco-2 Cells; Mice, Inbred C57BL; Colitis; Dextran Sulfate. |
| Ameliorative Effects of Larazotide Acetate on Intestinal Permeability and Bacterial Translocation in Acute Pancreatitis Model in Rats pmid:38441784 | 2024 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Intestinal Mucosa; Rats, Sprague-Dawley; Intestinal Diseases; Pancreatitis; Acute Disease. |
| Larazotide acetate for treatment of celiac disease: A systematic review and meta-analysis of randomized controlled trials pmid:34339872 | 2022 | Meta-Analysis, Systematic Review | other | Not stated | Indexed as meta-analysis, systematic review. study model from MeSH "Humans" with no interventional publication type. subject headings: Celiac Disease; Oligopeptides; Randomized Controlled Trials As Topic; Glutens; Diet, Gluten-Free. |
| Tight junction regulation in celiac disease: role of larazotide acetate pmid:33793152 | 2022 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Humans" with no interventional publication type. subject headings: Tight Junctions; Celiac Disease; Oligopeptides; Permeability. |
| Larazotide acetate: a pharmacological peptide approach to tight junction regulation pmid:33881350 | 2021 | Research Support, Non-U.S. Gov't, review-article | other | Not stated | Indexed as research support, non-u.s. gov't, review-article. study model from MeSH "Animals" with no rodent species heading. subject headings: Tight Junctions; Celiac Disease; Oligopeptides; Permeability; Tight Junction Proteins. |
| The Therapeutic use of the Zonulin Inhibitor AT-1001 (Larazotide) for a Variety of Acute and Chronic Inflammatory Diseases pmid:33397225 | 2021 | Review | other | Not stated | Indexed as review. study model from MeSH "Humans" with no interventional publication type. subject headings: Intestinal Mucosa; Tight Junctions; Oligopeptides; Haptoglobins; Protein Precursors. |
| Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation pmid:34502335 | 2021 | research-article | other | Not stated | Indexed as research-article. study model from MeSH "Humans" with no interventional publication type. subject headings: Cell Line; Herpesvirus 3, Human; Cytomegalovirus; Peptides; Oligopeptides. |
| Larazotide acetate induces recovery of ischemia-injured porcine jejunum via repair of tight junctions pmid:33886649 | 2021 | Research Support, Non-U.S. Gov't, research-article | rodent | Not stated | Indexed as research support, non-u.s. gov't, research-article. study model from MeSH "Disease Models, Animal". subject headings: Intestinal Mucosa; Jejunum; Tight Junctions; Swine; Ischemia. |
| Effects of larazotide acetate, a tight junction regulator, on the liver and intestinal damage in acute liver failure in rats pmid:34791921 | 2021 | Journal Article | rodent | Not stated | Indexed as journal article. study model from MeSH "Rats". subject headings: Intestines; Liver; Tight Junctions; Rats, Wistar; Liver Failure, Acute. |
| In vivo assessment of a delayed release formulation of larazotide acetate indicated for celiac disease using a porcine model pmid:33844694 | 2021 | Research Support, Non-U.S. Gov't, research-article | other | Not stated | Indexed as research support, non-u.s. gov't, research-article. study model from MeSH "Animals" with no rodent species heading. subject headings: Duodenum; Jejunum; Swine; Celiac Disease; Oligopeptides. |
| [Larazotide as an option in case of failure of a gluten-free diet] pmid:26983338 | 2016 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Humans" with no interventional publication type. subject headings: Celiac Disease; Oligopeptides; Treatment Failure; Diet, Gluten-Free. |
Where this page sits
Compound page: Larazotide. Class: Tissue repair peptides.
Retrieved 2026-10-12.
Sources
- PubChem Compound Summary for CID 9810532, Larazotide. PubChem, National Library of Medicine (2026). pubchem:9810532
- Drugs@FDA application register query for this compound, no application records returned. U.S. Food and Drug Administration, openFDA drugsfda endpoint (2026). fda:larazotide
- Larazotide acetate regulates epithelial tight junctions in vitro and in vivo. Peptides (2012). pmid:22401908
- Larazotide acetate promotes tight junction assembly in epithelial cells. Peptides (2012). pmid:22401910
- Larazotide acetate: a pharmacological peptide approach to tight junction regulation. American journal of physiology. Gastrointestinal and liver physiology (2021). pmid:33881350
- A randomized, double-blind study of larazotide acetate to prevent the activation of celiac disease during gluten challenge. The American journal of gastroenterology (2012). pmid:22825365
- Larazotide acetate in patients with coeliac disease undergoing a gluten challenge: a randomised placebo-controlled study. Alimentary pharmacology & therapeutics (2013). pmid:23163616
- Larazotide acetate for persistent symptoms of celiac disease despite a gluten-free diet: a randomized controlled trial. Gastroenterology (2015). pmid:25683116
- Larazotide acetate for treatment of celiac disease: A systematic review and meta-analysis of randomized controlled trials. Clinics and research in hepatology and gastroenterology (2022). pmid:34339872
- <i>In silico</i> Analysis Revealed Potential Anti-SARS-CoV-2 Main Protease Activity by the Zonulin Inhibitor Larazotide Acetate. Frontiers in chemistry (2020). pmid:33520943
- Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation. International journal of molecular sciences (2021). pmid:34502335
- The Therapeutic use of the Zonulin Inhibitor AT-1001 (Larazotide) for a Variety of Acute and Chronic Inflammatory Diseases. Current medicinal chemistry (2021). pmid:33397225
On each stated value was matched to the record cited for it. That is record matching, not an appraisal of the research. Compiled and checked by: Peptide Monographs editorial desk. No qualified clinical reviewer.