Research records indexed for Melanotan II
This page carries 12 of the 199 records that the literature query returned for Melanotan II, selected by citation count and preferring records that name the compound in their title. It is a selection, not a complete index, and the 187 records it does not carry are not represented here. Every row resolves to a real identifier and names the study model, so no finding reads as a human claim by default. The compound page is Melanotan II.
Indexed records
| Record | Year | Study type | Model | n as stated | What it reported |
|---|---|---|---|---|---|
| Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism pmid:30629642 | 2019 | Research Support, Non-U.S. Gov't, research-article | rodent | Not stated | Indexed as research support, non-u.s. gov't, research-article. study model from MeSH "Mice, Inbred C57bl". subject headings: Mice, Inbred C57BL; Peptides, Cyclic; Alpha-MSH; Receptor, Melanocortin, Type 4; Behavior, Animal. |
| Evidence that Melanocortin Receptor Agonist Melanotan-II Synergistically Augments the Ability of Naltrexone to Blunt Binge-Like Ethanol Intake in Male C57BL/6J Mice pmid:26108334 | 2015 | research-article, Research Support, U.S. Gov't, Non-P.H.S. | rodent | Not stated | Indexed as research-article, research support, u.s. gov't, non-p.h.s.. study model from MeSH "Mice, Inbred C57bl". subject headings: Mice, Inbred C57BL; Ethanol; Naltrexone; Peptides, Cyclic; Alpha-MSH. |
| Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet pmid:24771717 | 2015 | Validation Study | other | Not stated | Indexed as validation study. study model from assigned MeSH headings do not state a study model. subject headings: Peptides, Cyclic; Alpha-MSH; Chromatography, Liquid; Internet; Tandem Mass Spectrometry. |
| The medial preoptic nucleus as a site of the thermogenic and metabolic actions of melanotan II in male rats pmid:24808495 | 2014 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Preoptic Area; Dorsomedial Hypothalamic Nucleus; Rats, Wistar; Peptides, Cyclic; Alpha-MSH. |
| Melanoma associated with the use of melanotan-II pmid:24355990 | 2014 | Journal Article | other | Not stated | Indexed as journal article. study model from MeSH "Humans" with no interventional publication type. subject headings: Melanoma; Skin Neoplasms; Peptides, Cyclic; Alpha-MSH; Sunbathing. |
| Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency pmid:22761160 | 2012 | Research Support, Non-U.S. Gov't, research-article | rodent | Not stated | Indexed as research support, non-u.s. gov't, research-article. study model from MeSH "Mice, Knockout". subject headings: Rhombencephalon; Neurons; Mice, Knockout; Peptides, Cyclic; Leptin. |
| Melanotan II injection resulting in systemic toxicity and rhabdomyolysis pmid:23121206 | 2012 | Case Reports | other | Not stated | Indexed as case reports. study model from MeSH "Humans" with no interventional publication type. subject headings: Kidney; Rhabdomyolysis; Poisoning; Acute Disease; Peptides, Cyclic. |
| Nanostructured porous silicon microparticles enable sustained peptide (Melanotan II) delivery pmid:20965250 | 2011 | Comparative Study, Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as comparative study, research support, non-u.s. gov't. study model from MeSH "Mice, Inbred Balb C". subject headings: Mice, Inbred BALB C; Mice, Inbred DBA; Rats, Wistar; Silicon; Peptides, Cyclic. |
| Melanocortinergic activation by melanotan II inhibits feeding and increases uncoupling protein 1 messenger ribonucleic acid in the developing rat pmid:17412803 | 2007 | Research Support, N.I.H., Extramural | rodent | Not stated | Indexed as research support, n.i.h., extramural. study model from MeSH "Rats". subject headings: Stomach; Gastric Mucosa; Hypothalamus; Animals, Suckling; Peptides, Cyclic. |
| The melanocortin agonist, melanotan II, enhances proceptive sexual behaviors in the female rat pmid:17113634 | 2006 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Rats". subject headings: Rats, Long-Evans; Peptides, Cyclic; Estradiol; Progesterone; Alpha-MSH. |
| Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice pmid:15971058 | 2005 | Research Support, Non-U.S. Gov't | rodent | Not stated | Indexed as research support, non-u.s. gov't. study model from MeSH "Mice, Inbred C57bl". subject headings: Liver; Mice, Inbred C57BL; Insulin Resistance; Peptides, Cyclic; Corticosterone. |
| Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression pmid:15225137 | 2004 | Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S. | rodent | Not stated | Indexed as research support, u.s. gov't, p.h.s., research support, u.s. gov't, non-p.h.s.. study model from MeSH "Rats". subject headings: Muscle, Skeletal; Hypothalamus; Rats, Sprague-Dawley; Obesity; Peptides, Cyclic. |
Where this page sits
Compound page: Melanotan II. Class: Melanocortin receptor peptides.
Retrieved 2026-10-10.
Sources
- PubChem Compound Summary for CID 92432, melanotan-II. PubChem, National Library of Medicine (2026). pubchem:92432
- Drugs@FDA application register query for this compound, no application records returned. U.S. Food and Drug Administration, openFDA drugsfda endpoint (2026). fda:melanotan-ii
- Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study. Life Sci (1996). pmid:8637402
- Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res (2000). pmid:11035391
- The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat. J Neuroendocrinol (2003). pmid:12535159
- Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression. J Endocrinol (2004). pmid:15225137
- Nanostructured porous silicon microparticles enable sustained peptide (Melanotan II) delivery. Eur J Pharm Biopharm (2011). pmid:20965250
- Afamelanotide for Erythropoietic Protoporphyria. N Engl J Med (2015). pmid:26132941
On each stated value was matched to the record cited for it. That is record matching, not an appraisal of the research. Compiled and checked by: Peptide Monographs editorial desk. No qualified clinical reviewer.